Canadian Scientists Discover Gene for Depression

Canadian scientists have identified a gene that makes some people susceptible to major depressive disorders. Speaking at the Forum of European Neuroscience today (9 July), Professor Nicholas Barden explained, “This is a major breakthrough in the realm of psychiatry and will have groundbreaking implications for diagnosis and the development of new anti-depressant treatment.”

It has been known for many years that genetic factors are at the base of depression and bipolar disorder, but the complex molecular networks involved remain unknown. “The actual gene, known as P2RX7, is found in humans and animals and is responsible for depression. It has taken many years to find,” said neuroscientist, Professor Barden from CHUL Research Centre in Quebec. Finding it is highly significant in uncovering the molecular pathways involved in depression. The results were published in May 2006 American Journal of Medical Genetics